DETERMINE
Eligibility
Persons may be eligible to participate in this trial if they meet the following criteria.
- Evidence of CAD
- Prior MI or LV Dysfunction
- 18 years of age or older
Complete Title
Defibrillators to Reduce Risk by Magnetic Resonance Imaging Evaluation
Purpose
To determine if Implantable Cardioverter Defibrillator therapy in combination with medical therapy in patients with an infarct size greater than or equal to 10 percent of the left ventricular mass improves long term survival compared to medical therapy alone.
Summary
Several clinical trials have previously shown that the ICD reduces mortality in patients with coronary artery disease who had not yet suffered a life threatening arrhythmia and who were selected based either on the results of EP testing or degree of left ventricular dysfunction.
Sponsor(s)